Architect of India’s first and world’s second test tube baby

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1931, 16th January - Born in Hazaribag, Bihar, India

1955 - Obtained M.B.B. S. from National Medical College, Calcutta. Stood First in Gynecology and also obtained Hemangini scholarship. Obtained B.Sc. (Hons.) in Physiology from Calcutta University.

1958 - PhD. From Calcutta University in Reproductive Physiology under the stewardship of Prof. Sachchidananda Banerjee.

1960 - Marriage with Namita and left for U.K under Colombo Plan to study Endocrine Physiology.

1967 - PhD. from Edinburgh in Reproductive Endocrinology, Developed method for estimation of Hormone (LH). He worked at the Clinical Endocrinology Research Institute with Prof. John A. Loraine and obtained his Ph.D. In his research work a new method for assay of LH was found out. In those days no reliable method was available. The Technique depends on ovarian cholesterol depletion of intact immature rats pretreated with PMSG & HCG. He also worked at the Royal Infirmary, Edinburgh.

1967 to 1975 - Lecturer, Reader and Professor of Physiology, NRS Medical College, Calcutta. Fundamental Research on the origin of HCG, which was postulated by Theodore Langhans as far back in 1870. He contradicted the view and established that it is of decidual origin rather than trophoblastic in origin. Hence he had to play with the embryos and early stage foetus, which helped him in creating Test Tube Babies. Fundamental work on the use of Testosterone in the management of female infertility. Outstanding hypotheses that stress is related to female infertility, which was presented at the International Conference on physiological sciences held in Paris in July 1977. Later workers are now confirming such relations.

1978, 17th August - Invited by the Rotary club of Belur to speak on Test Tube Baby.

1978, 3rd October - Birth of India's first Test Tube Baby was announced. His method was different from that followed by Steptoe & Edwards and it was also the World's first Test Tube Baby from frozen and thawed embryo. He did not undervalue the Indian Science and published his paper in Indian Journal of Cryogenics and presented his findings in the Indian Science Congress, in January 1979.

He discussed his experiment in the "Fifth International Congress on hormonal Steroids 1978" held at New Delhi in November - December 1978. He also discussed the matter with Professor John Biggers of the Laboratory of Human Reproduction, Harvard Medical School,. USA and Prof. B. B. Sexena Professor of Bio-Chemistry and Endocrinology of the Cornell University Medical School in the USA and Professor Kenneth Ryan Professor of Gynecology of Havard. He was invited by the Benaras Hindu University to speak on the subject of embryo transfer. He also talked on the subject at Gauhati Medical College at the conference of the Gauhati Obstetrical and Gynecological Society - where he was presented with a "Manpatra" or a scroll of honour.

1978, December - Govt. of West Bengal set up an Enquiry Committee which did not acknowledge his claim. As no physiological or biochemical techniques including DNA fingerprinting can distinguish between in - vivo and in - vitro fertilised normal baby, Dr. Subhas Mukherjee categorically stated to all concerned people that he cannot provide a sure proof for his work on IVF and ET. But he also asserted that if there was a genetic marker, through a surrogate, then proof will be obviously established. Even after these long years, as far is known, no country in the world has accepted a legal connotation of a test tube baby on the municipal birth certificate. Some professional bodies also heckled him in some meetings. He was denied Passport to go to Japan where he was invited to speak on IVF & ET. He was later transferred to the Eye dept. of Medical College, Calcutta in June 1981.

1980 - He had an heart attack and was transferred to RG Kar Medical College, Calcutta.

1981, 19th June - Dr. Subhas Mukherjee committed suicide.



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